Item no. |
BOS-EK0962 |
Manufacturer |
Boster
|
Amount |
96 wells/kit, with removable strips. |
Category |
|
Type |
Elisa-Kit |
Applications |
ELISA |
Specific against |
Human |
Sensitivity |
<10 pg/ml |
ECLASS 10.1 |
32160605 |
ECLASS 11.0 |
32160605 |
UNSPSC |
41116126 |
Alias |
Insulin-like growth factor-binding protein 6;IBP-6;IGF-binding protein 6;IGFBP-6;IGFBP6;IBP6; |
Available |
|
Manufacturers Product Category |
PicoKine® ELISA Kits |
Manufacturers Research Category |
Growth Factors/Hormones, Lipid Signaling, Signal Transduction, Signaling Pathway |
Short Description |
Human IGFBP6 ELISA Kit PicoKine® (96 Tests). Quantitate Human IGFBP6 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. |
Description |
Human IGFBP6 ELISA Kit PicoKine® (96 Tests). Quantitate Human IGFBP6 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. |
Background |
Insulin-like growth factor-binding protein 6 (IGFBP6) is a protein that in humans is encoded by the IGFBP6 gene. The IGFBP6 gene is mapped to chromosome 12. In all, it has contained 216 amino acid protein with a calculated molecular mass of 22, 847, The human keratinocyte cell line HaCat secretes IGFBP6 as an autocrine growth inhibitor. Recombinant IGFBP6 was also shown to inhibit growth of HaCat cells and other keratinocyte cell lines. |
Gene Name |
IGFBP6 |
Application Details |
Dilution ratio of 1:1000, concentration in serum and plasma is 197-438 ng/ml. |
Immunogen |
Expression system for standard: NS0; Immunogen sequence: A25-G240 |
Cross-reactivity |
There is no detectable cross-reactivity with other relevant proteins. |
Sample Type |
cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). |
Capture antibody|Detection antibody |
monoclonal antibody from mouse|polyclonal antibody from goat |
Storage |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
Anticoagulant |
heparin or EDTA |
Gene Full Name |
Insulin-like growth factor-binding protein 6 |
Molecular Weight |
25322 MW |
Protein Function |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. |
Subcellular Localization |
Secreted. |
Protein Name |
Insulin-like growth factor-binding protein 6 |
Sequence Similarities |
Contains 1 IGFBP N-terminal domain. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.