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Human Beta Nerve Growth Factor / NGF Beta / NGFB ELISA Kit PicoKine®

Human Beta Nerve Growth Factor / NGF Beta / NGFB ELISA Kit PicoKine®

Item no.	BOS-EK0469
Manufacturer	Boster
Amount	96 wells/kit, with removable strips.
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling ELISA ELISA & Immunoassays ELISA Kits Immunoassay By Organ Colorectal Cancer
Type	Elisa-Kit
Applications	ELISA
Specific against	Human
Sensitivity	<15 pg/ml
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Beta-nerve growth factor;Beta-NGF;NGF;NGFB;
Available
Manufacturers Product Category	PicoKine® ELISA Kits
Manufacturers Research Category	Growth and Development, Mesenchymal Stem Cells, Neural Stem Cells, Neurology Process, Neuroscience, Stem Cells, Surface Molecules
Short Description	Human Beta Nerve Growth Factor / NGF Beta / NGFB ELISA Kit PicoKine® (96 Tests). Quantitate Human NGF in cell culture supernatants and serum. Sensitivity: 15 pg/ml.
Description	Human Beta Nerve Growth Factor / NGF Beta / NGFB ELISA Kit PicoKine® (96 Tests). Quantitate Human NGF in cell culture supernatants and serum. Sensitivity: 15 pg/ml.
Background	Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male mouse submaxillary gland (MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130, 000-molecular weight (Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis. The standard product used in this kit is human 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.
Gene Name	NGF
Application Details	Dilution ratio of 1:1, concentration in serum is less than the lowest standard, 31.2 pg/ml.
Immunogen	Expression system for standard: NS0; Immunogen sequence: S122-A241
Cross-reactivity	There is no detectable cross-reactivity with other relevant proteins.
Sample Type	cell culture supernatants and serum.
Capture antibody\|Detection antibody	polyclonal antibody from rabbit\|polyclonal antibody from goat
Storage	Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Gene Full Name	Beta-nerve growth factor
Molecular Weight	26959 MW
Protein Function	Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177)..
Subcellular Localization	Secreted.
Protein Name	Beta-nerve growth factor
Sequence Similarities	Belongs to the NGF-beta family.

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