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Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody

Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody

Item no.	BOS-P00097-1
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC
Clone	EIH-13
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Microtubule-associated protein tau;Neurofibrillary tangle protein;Paired helical filament-tau;PHF-tau;MAPT;MAPTL, MTBT1, TAU;
Available
Manufacturers Product Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturers Research Category	Alzheimer's Disease, Cell Type Marker, Cytoskeleton, Cytoskeleton/ECM, Microtubules, Neurodegenerative Disease, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction
Short Description	Boster Bio Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody catalog # P00097-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody catalog # P00097-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Gene Name	MAPT
Application Details	WB 1:500-1:2000 IHC 1:50-1:200 IP 1:50
Clonality	Monoclonal
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Immunogen	A synthesized peptide derived from human Phospho-Tau (T231)
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Microtubule-associated protein tau
Molecular Weight	78928 MW
Protein Function	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization..
Subcellular Localization	Cytoplasm, cytosol. Cell membrane ; Peripheral membrane protein ; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
Tissue Specificity	Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 8/30/2024

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