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Anti-Human Cytochrome C DyLight® 550 conjugated CYCS Antibody(monoclonal, 15F10)

Anti-Human Cytochrome C DyLight® 550 conjugated CYCS Antibody(monoclonal, 15F10)

Item no.	BOS-M03529-Dyl550
Manufacturer	Boster
Amount	100 ug/vial
Category	Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	FC
Clone	15F10
Specific against	Human
Host	Mouse
Isotype	IgG1
Conjugate/Tag	DyLight 500
Citations	1. Garcia-Heredia JM, et al. Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome. FEBS Lett, 2012 Jan 20. <br/>2. Rajagopal BS, et al. The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant. Biochem J, 2013 Dec 15.<br/>3. Simon M, et al. Versatility of non-native forms of human cytochrome c: pH and micellar concentration dependence. J Biol Inorg Chem, 2013 Jan.<br/>
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cytochrome c; CYCS; CYC
Available
Specificity	No cross reactivity with other proteins.
Manufacturers Product Category	Primary Antibodies, Mouse Monoclonal Antibodies
Manufacturers Research Category	Apoptosis, Apoptotic Markers, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Cell Death, Cytochromes, Energy Metabolism, Energy Transfer Pathways, Integration Of Energy, Integration Of Energy Metabolism, Invasion/Microenvironment, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Oxidative Phosphorylation, Pathways and Processes, Signal Transduction
Short Description	Boster Bio Anti-Human Cytochrome C DyLight® 550 conjugated CYCS Antibody (monoclonal, 15F10) catalog # M03529-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
Description	Boster Bio Anti-Human Cytochrome C DyLight® 550 conjugated CYCS Antibody (monoclonal, 15F10) catalog # M03529-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
Background	CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
Gene Name	CYCS
Application Details	Flow Cytometry, 1-3μg/1x10⁶ cells
Clonality	Monoclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Immunogen	E.coli-derived human Cytochrome C recombinant protein (Position: G2-E105). Human Cytochrome C shares 91% amino acid (aa) sequence identity with both mouse and rat Cytochrome C.
Cross-reactivity	No cross-reactivity with other proteins.
Storage	At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Gene Full Name	cytochrome c, somatic
Protein Function	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Subcellular Localization	Mitochondrion intermembrane space. Loosely associated with the inner membrane.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/vial

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Delivery expected until 8/30/2024

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