Item no. |
BOS-M01432-3 |
Manufacturer |
Boster
|
Amount |
100 ul |
Category |
|
Type |
Antibody Primary |
Format |
Liquid |
Applications |
WB, IHC |
Clone |
RM328 |
Specific against |
Human (Homo sapiens) |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Keratin, type I cytoskeletal 14;Cytokeratin-14;CK-14;Keratin-14;K14;KRT14; |
Available |
|
Manufacturer - Category |
Primary Antibodies, Monoclonal Antibodies, Rabbit Monoclonal Antibodies, 2279 |
Manufacturer - Isotype |
Rabbit IgG |
Storage Conditions |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. |
Observed Molecular Weight |
51561 MW |
Clonality |
Monoclonal |
Application Details |
Immunohistochemistry (IHC): 1:1000-1:2000 dilution
WB: 1:1000-1:2000 dilution. |
Manufacturer - Gene Name |
KRT14 |
Gene Full Name |
Keratin, type I cytoskeletal 14 |
Immunogen |
A peptide corresponding to C-terminus of human Cytokeratin-14 |
Contents |
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
Purification |
Protein A affinity purified from an animal origin-free culture supernatant |
Concentration |
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Protein Function |
The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. |
Subcellular Localization |
Cytoplasm. Nucleus. Expressed in both as a filamentous pattern. |
Short Description |
Boster Bio Anti-CK-14 (Cytokeratin-14) KRT14 Rabbit Monoclonal Antibody, Clone#RM328 (Catalog # M01432-3). Tested in IHC, WB applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-CK-14 (Cytokeratin-14) KRT14 Rabbit Monoclonal Antibody, Clone#RM328 (Catalog # M01432-3). Tested in IHC, WB applications. This antibody reacts with Human. |
Tissue Specificity |
Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. |
Predicted Reactivity |
Mouse, Rat |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.