Anti-CD74 (B-Cell Marker) Monoclonal Antibody

Primary Antibodies, Monoclonal Antibodies

Boster Bio Anti-CD74 (B-Cell Marker) Monoclonal Antibody (Catalog # M01340-1). Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Baboon, Mouse.

This monoclonal antibody recognizes a protein of ~35kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).

Monoclonal

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

SU-DHL-4 lymphoma cells

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.