« Back
Home /
Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody

Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody

Item no.	BOS-M01148
Manufacturer	Boster
Amount	100 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	FC, IF, IHC, ELISA
Clone	LPFS2/1611
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD27 antigen;CD27L receptor;T-cell activation antigen CD27;T14;Tumor necrosis factor receptor superfamily member 7;CD27;CD27;TNFRSF7;
Available
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Observed Molecular Weight	29137 MW
Clonality	Monoclonal
Application Details	ELISA (For coating, order antibody without BSA) Flow Cytometry (1-2ug/million cells) Immunofluorescence (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Manufacturer - Gene Name	CD27
Gene Full Name	CD27 antigen
Background	Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
Immunogen	Recombinant full-length human CD27 protein
Contents	Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Purification	200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Concentration	Purified antibody with BSA and azide at 200ug/ml
Manufacturer - Research Category	Adaptive Immunity, Cancer, Cytokines, Hematopoietic Progenitors, Immunology, Innate Immunity, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage, TNF Superfamily, Tumor Immunology
Protein Function	Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Subcellular Localization	Cell Surface
Short Description	Boster Bio Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody (Catalog # M01148). Tested in ELISA, Flow Cytometry, IF, IHC applications. This antibody reacts with Human.
Description	Boster Bio Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody (Catalog # M01148). Tested in ELISA, Flow Cytometry, IF, IHC applications. This antibody reacts with Human.
Tissue Specificity	Found in most T-lymphocytes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 5/1/2025

Express Delivery: Save 10 days

Compare

Add to wishlist

Recommend by mail