Item no. |
BOS-M00851 |
Manufacturer |
Boster
|
Amount |
100 ug |
Category |
|
Type |
Antibody Monoclonal |
Format |
Liquid |
Applications |
FC, IF, IHC |
Clone |
SPM106 |
Specific against |
Human (Homo sapiens) |
Host |
Mouse |
Isotype |
IgG2b Kappa |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Somatotropin;Growth hormone;GH;GH-N;Growth hormone 1;Pituitary growth hormone;GH1; |
Available |
|
Manufacturer - Category |
Primary Antibodies, Monoclonal Antibodies, 2279 |
Storage Conditions |
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
Observed Molecular Weight |
24847 MW |
Clonality |
Monoclonal |
Application Details |
Flow Cytometry (1-2ug/million cells) Immunofluorescence (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined. |
Manufacturer - Gene Name |
GH1 |
Gene Full Name |
Somatotropin |
Background |
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly). |
Immunogen |
A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary) |
Contents |
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Purification |
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G. |
Concentration |
Purified antibody with BSA and azide at 200ug/ml |
Manufacturer - Research Category |
Developmental Biology, Growth Factors/Hormones, Signal Transduction |
Protein Function |
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. |
Subcellular Localization |
Cytoplasmic |
Short Description |
Boster Bio Anti-Growth Hormone (Pituitary Marker) GH1 Monoclonal Antibody (Catalog # M00851). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-Growth Hormone (Pituitary Marker) GH1 Monoclonal Antibody (Catalog # M00851). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.