Manufacturer |
Boster
|
Category |
|
Type |
Antibody Monoclonal |
Specific against |
Human, Mouse |
Clone |
GEO-3 |
Isotype |
IgG |
Format |
Liquid |
Applications |
WB, IF, IP, IHC, ICC |
Amount |
100 ul |
Host |
Rabbit |
Item no. |
BOS-M00080 |
Targets |
CASP9 |
eClass 6.1 |
32160702 |
eClass 9.0 |
42030590 |
Available |
|
Alias |
Caspase-9;CASP-9;3.4.22.62;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;APAF-3;ICE-like apoptotic protease 6;ICE-LAP6;Caspase-9 subunit p35;Caspase-9 subunit p10;CASP9;MCH6; |
Manufacturers Product Category |
Primary Antibodies, Rabbit Monoclonal Antibodies |
Manufacturers Research Category |
Apoptosis, Apoptotic Markers, Cancer, Caspases, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes |
Short Description |
Boster Bio Anti-Caspase-9 CASP9 Rabbit Monoclonal Antibody catalog # M00080. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse. |
Description |
Boster Bio Anti-Caspase-9 CASP9 Rabbit Monoclonal Antibody catalog # M00080. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse. |
Gene Name |
CASP9 |
Application Details |
WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 |
Clonality |
Monoclonal |
Concentration |
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Contents |
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Immunogen |
A synthesized peptide derived from human Caspase-9 |
Purification |
Affinity-chromatography |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Caspase-9 |
Molecular Weight |
46281 MW |
Protein Function |
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP- ribose) polymerase (PARP). |
Tissue Specificity |
Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.