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Anti-RAB7L1 RAB29 Antibody

Anti-RAB7L1 RAB29 Antibody

Item no.	BOS-A08450
Manufacturer	Boster
Amount	100ul
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Targets for Rodent Neurosciences Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Rab Subfamily
Type	Antibody
Format	Liquid
Applications	WB
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ras-related protein Rab-7L1;Rab-7-like protein 1;Ras-related protein Rab-29;RAB29;RAB7L1;
Available
Manufacturers Product Category	Primary Antibodies
Short Description	Boster Bio Anti-RAB7L1 RAB29 Antibody (Catalog # A08450). Tested in WB applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-RAB7L1 RAB29 Antibody (Catalog # A08450). Tested in WB applications. This antibody reacts with Human, Mouse.
Gene Name	RAB29
Clonality	Polyclonal
Concentration	1 mg/ml
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Details	Western blotting: 1:500~1:3000
Immunogen	Synthesized peptide derived from internal of human RAB7L1.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Ras-related protein Rab-7L1
Molecular Weight	23155 MW
Protein Function	Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection..
Subcellular Localization	Cell membrane ; Lipid-anchor ; Cytoplasmic side. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Vacuole. Cytoplasm, cytoskeleton. Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (By similarity). Colocalizes with GM130 at the Golgi apparatus (PubMed:22042847). Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus (PubMed:22042847). Colocalizes with TGN46 at the trans-Golgi network (TGN) (PubMed:24788816). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery (PubMed:22042847)..
Tissue Specificity	Ubiquitous..

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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