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Anti-Dkk3 Antibody

Anti-Dkk3 Antibody

Item no.	BOS-PB9566
Manufacturer	Boster
Amount	100 ug/vial
Category	Oncology Neuroscience Neural Lineage Markers Antibodies Primary Antibodies By Organ Heart & Blood Cancer Glial Cell Markers
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, IHC, ELISA
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
Citations	1. "Entrez Gene: DKK3 dickkopf homolog 3 (Xenopus laevis)". <br/><br/>2. Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA (Dec 1999). "Functional and structural diversity of the human Dickkopf gene family". Gene 238 (2): 301–13. <br/><br/>3. Roman-Gomez J, Jimenez-Velasco A, Agirre X et al. (2004). "Transcriptional silencing of the Dickkopfs-3 (Dkk-3) gene by CpG hypermethylation in acute lymphoblastic leukaemia". Br. J. Cancer 91 (4): 707–13. <br/><br/>
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Dickkopf 3 antibody, Dickkopf 3 homolog (Xenopus laevis) antibody, Dickkopf 3 homolog antibody, Dickkopf homolog 3 antibody, Dickkopf related protein 3 antibody, Dickkopf related protein 3 Precursor antibody, Dickkopf WNT signaling pathway inhibitor 3 antibody, Dickkopf, Xenopus, homolog of, 3 antibody, Dickkopf-3 antibody, Dickkopf-related protein 3 antibody, Dickkopf3 antibody, DKK 3 antibody, Dkk-3 antibody, DKK3 antibody, DKK3_HUMAN antibody, hDkk 3 antibody, hDkk-3 antibody, hDkk3 antibody, Regulated in glioma antibody, REIC antibody, RIG antibody, RIG-like 5-6 antibody, RIG-like 7-1 antibody
Available
Specificity	No cross reactivity with other proteins.
Background	Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Description short	Rabbit IgG polyclonal antibody for Dickkopf-related protein 3(DKK3) detection. Tested with WB, IHC-P, ELISA in Human; Mouse; Rat.
ELISA	Concentration: 0.1-0.5ug/ml; Tested Species: Human
Gene Full Name	dickkopf WNT signaling pathway inhibitor 3
Gene Name	DKK3
Immunogen	E. coli-derived human Dkk3 recombinant protein (Position: A22-D152). Human Dkk3 shares 85.5% amino acid (aa) sequence identity with mouse Dkk3.
Immunohistochemistry (Paraffin-embedded Section)	Concentration: 0.5-1ug/ml; Tested Species: Human, Mouse, Rat
Notes	Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Protein Name	Dickkopf-related protein 3
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Relevant detection systems	Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Storage	At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Western blot	Concentration: 0.1-0.5ug/ml; Tested Species: Human, Mouse, Rat

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.