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Anti-OPCML Antibody

Anti-OPCML Antibody

Item no.	BOS-PA1131
Manufacturer	Boster
Amount	100 ug/vial
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GM181 antibody, IgLON family member 1 antibody, IGLON1 antibody, OBCAM antibody, OPCM antibody, OPCM_HUMAN antibody, OPCML antibody, Opiate binding cell adhesion molecule antibody, Opioid binding cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule-like antibody, Opioid binding protein/cell adhesion molecule-like preprotein antibody, Opioid-binding cell adhesion molecule antibody, Opioid-binding protein/cell adhesion molecule antibody
Similar products	GM181 antibody, IgLON family member 1 antibody, IGLON1 antibody, OBCAM antibody, OPCM antibody, OPCM_HUMAN antibody, OPCML antibody, Opiate binding cell adhesion molecule antibody, Opioid binding cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule-like antibody, Opioid binding protein/cell adhesion molecule-like preprotein antibody, Opioid-binding cell adhesion molecule antibody, Opioid-binding protein/cell adhesion molecule antibody
Available
Background	Opioid-binding protein/cell adhesion molecule-like(OPCML), (also called opioid-binding cell adhesion molecule(OBCAM). OPCML is a member of the IgLON family of immunoglobulin(Ig) domain-containing glycosylphosphatidylinositol(GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC. The OPCML gene comprises 7 exons, spans approximately 600 kb, and is transcribed from telomere to centromere . And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor; more likely, it plays an important accessory role in opioid receptor function.
Concentration	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Cross reactivity	No cross reactivity with other proteins
Description	Rabbit IgG polyclonal antibody for Opioid-binding protein/cell adhesion molecule(OPCML) detection. Tested with WB, IHC-P in Human; Mouse; Rat.
Gene full name	Opioid-binding protein/cell adhesion molecule
Gene name	OPCML
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human OPCML(294-312aa YTCVATNKLGNTNASITLY), identical to the related rat and mouse sequences.
MW	38008 MW
Predicted reactivity	Hamster
Protein function	Binds opioids in the presence of acidic lipids; probably involved in cell contact.
Protein name	Opioid-binding protein/cell adhesion molecule(OBCAM/OPCML/Opioid-binding cell adhesion molecule)
Purification	Immunogen affinity purified.
Recommended detection ystems	Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Research category	\|neuroscience\|cell adhesion proteins\|membrane proteins\| neuroscience\|neurotransmission\|receptors / channels\|gpcr\|opioid receptors\| cancer\|oncoproteins/suppressors\|tumor suppressors
Sequence similarities	Belongs to the immunoglobulin superfamily. IgLON family.
Storage	At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time.Avoid repeated freezing and thawing.
Subcellular localization	Cell membrane ; Lipid-anchor, GPI-anchor .

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.