ND3 polyclonal antibody

NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.

P03899

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

ca. 13 kDa

NADH-ubiquinone oxidoreductase chain 3 (EC:1.6.5.3), NADH dehydrogenase subunit 3, Mtnd3, mt-Nd3, Nd3