Item no. |
BS1406-50 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
NADH-ubiquinone oxidoreductase chain 3 (EC:1.6.5.3), NADH dehydrogenase subunit 3, Mtnd3, mt-Nd3, Nd3 |
Available |
|
Buffer composition |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. |
Background |
NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease. |
Application info |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Swiss-Prot |
P03899 |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
ND3 pAb detects endogenous levels of ND3 protein. |
BiowMW |
ca. 13 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
NADH-ubiquinone oxidoreductase chain 3 (EC:1.6.5.3), NADH dehydrogenase subunit 3, Mtnd3, mt-Nd3, Nd3 |
Immunogen |
A synthetic peptide corresponding to amino acids 21-34 of Mouse ND3. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.