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IL1RAP polyclonal antibody

IL1RAP polyclonal antibody

Item no.	BS7753-50
Manufacturer	Bioworld Technology, Inc
Amount	50ul
Category	Neuroscience Neuroinflammation Metabolism Diabetes Antibodies Obesity Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C3orf13, IL 1 receptor accessory protein, IL 1R 3, IL 1R3, IL 1RAcP, IL 1RAP, IL-1 receptor accessory protein, IL-1R-3, IL-1R3, IL-1RAcP, IL1 receptor accessory protein, IL1AP_HUMAN, IL1R3, IL1RAcP, Il1rap, Interleukin 1 Accessory Protein,
Similar products	IL1RAP
Available
Swiss-Prot	Q9NPH3
Application all	WB: 1:500ca.1:2000 IHC: 1:50ca.1:200
Background	?Interleukin-1 (IL-1) is a key pro-inflammatory cytokine that has diverse actions in the brain as a regulator of host defense responses and a mediator of inflammation. Two major agonists, IL-1alpha and IL-1beta, bind to a single known functional type-1 IL-1 receptor (IL-1RI), which associates with the accessory protein (IL-1RAcP), resulting in signal transduction. IL-1F6, IL-1F8, and IL-1F9 signal through IL-1RAcP to activate NFCB. The membrane bound form of IL-1RAcP (mIL-1RAcP) facilitates signal transduction. Two alternatively spliced isoforms, soluble IL-1RAcP (sIL-1RAcP) and sIL-1RAcP-beta, which lack transmembrane and intracellular domains, can inhibit IL-1 signaling. Although both mIL-1RAcP and sIL-1RAcP mRNAs are widely expressed in human tissue, their relative proportions differ significantly in a tissue-specific manner.
Product	1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	IL1RAP pAb detects endogenous levels of IL1RAP protein.
BiowMW	ca. 66 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	C3orf13, IL 1 receptor accessory protein, IL 1R 3, IL 1R3, IL 1RAcP, IL 1RAP, IL-1 receptor accessory protein, IL-1R-3, IL-1R3, IL-1RAcP, IL1 receptor accessory protein, IL1AP_HUMAN, IL1R3, IL1RAcP, Il1rap, Interleukin 1 Accessory Protein, interleukin 1 receptor 3, Interleukin 1 receptor accessory protein, interleukin 1 receptor accessory protein beta, Interleukin-1 receptor 3, Interleukin-1 receptor accessory protein, hide
Immunogen	Recombinant full length Human IL1RAP.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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