Item no. |
BS7680-50 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
A inhibin subunit, A inhibin subunit precursor, IHA, INHA, INHA_HUMAN, Inhibin alpha chain, Inhibin alpha chain precursor, Inhibin alpha subunit, |
Similar products |
INHA |
Available |
|
Swiss-Prot |
P05111 |
Application all |
WB: 1:500ca.1:2000 IHC: 1:50ca.1:200 |
Background |
Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same alpha subunit, covalently linked to 1 of 2 distinct subunits, beta-alpha or beta-beta. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor beta (TGFbeta) superfamily of growth and differentiation factors. TGFbeta proteins affect a range of tissues and systems beyond their role in reproduction. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, placenta and, most notably, anterior pituitary. Inhibin alpha-subunit gene expression is down regulated in human prostate cancer, suggesting a tumor-suppressive role. The human Inhibin alpha gene maps to chromosome 2q33-q36. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
INHA pAb detects endogenous levels of INHA protein. |
BiowMW |
ca. 40 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
A inhibin subunit, A inhibin subunit precursor, IHA, INHA, INHA_HUMAN, Inhibin alpha chain, Inhibin alpha chain precursor, Inhibin alpha subunit, |
Immunogen |
Recombinant full length Human INHA. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.