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CYP46A1 polyclonal antibody

CYP46A1 polyclonal antibody

Item no.	BS71294-100
Manufacturer	Bioworld Technology, Inc
Amount	100ul
Category	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 5.1	32160702
ECLASS 6.1	32160702
ECLASS 8.0	32160702
ECLASS 9.0	32160702
ECLASS 10.0.1	32160702
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CP46, CYP46
Available
Buffer composition	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
Application info	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Swiss-Prot	Q9Y6A2
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	CYP46A1 polyclonal antibody detects endogenous levels of CYP46A1 protein.
BiowMW	ca. 57 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	CP46, CYP46
Immunogen	Recombinant protein of human CYP46A1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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