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Caspase-4 p20 (Q81) polyclonal antibody

Caspase-4 p20 (Q81) polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	BS7065-100
Targets	CASP4;;NAPSA
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	Caspase-4, CASP-4, ICE(rel)-II, Protease ICH-2, Protease TX, Caspase-4 subunit 1, CASP4, ICH2, Caspase 4, Caspase4
Swiss-Prot	P49662
Application all	WB: 1:500ca.1:1000
Background	A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks.
Product	1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	Caspase-4 p20 (Q81) pAb detects endogenous levels of Caspase-4 p20 protein.
WB	Western blot (WB) analysis of Caspase-4 p20 (Q81) pAb at 1:500 dilution Lane1:HepG2 cell lysate treated with colchicine Lane2:sp2/0 cell lysate treated with H2O2 Lane3:Rat kidney tissue lysate
BiowMW	ca. 20, 45 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Caspase-4, CASP-4, ICE(rel)-II, Protease ICH-2, Protease TX, Caspase-4 subunit 1, CASP4, ICH2, Caspase 4, Caspase4
Immunogen	Synthetic peptide, corresponding to amino acids 50-100 of Human Caspase 4.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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