Item no. |
BS70000-100 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, alpha-SMA, a-SMA, aSMA, SMA-alpha |
Similar products |
alpha-SMA |
Available |
|
Swiss-Prot |
P62736 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 IF: 1:50ca.1:200 |
Background |
Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
alpha-SMA pAb detects endogenous levels of Actin, aortic smooth muscle protein. |
WB |
Western blot analysis on Jurkat cells using alpha-SMA pAb, The lane on the left is blocked with the antigen-specific peptide. |
BiowMW |
ca. 45 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, alpha-SMA, a-SMA, aSMA, SMA-alpha |
Immunogen |
Recombinant full length Human alpha-SMA. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.