Manufacturer |
Bioworld Technology, Inc
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applications |
WB, IF |
Amount |
100ul |
Host |
Rabbit |
Item no. |
BS6996-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, Cytokeratin5, Short name=CK-5, CK5, Keratin-5, Keratin5, Keratin 5, Short name=K5, Type-II keratin Kb5, KRT5 |
Swiss-Prot |
P13647 |
Application all |
WB: 1:500ca.1:2000 |
Background |
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB). |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Cytokeratin 5 pAb detects endogenous levels of Cytokeratin 5 protein. |
WB |
Western blot analysis of Cytokeratin 5 polyclonal antibody |
IF |
Immunofluorescence analysis of Hela cells, using Cytokeratin 5 polyclonal antibody |
BiowMW |
ca. 62 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, Cytokeratin5, Short name=CK-5, CK5, Keratin-5, Keratin5, Keratin 5, Short name=K5, Type-II keratin Kb5, KRT5 |
Immunogen |
Recombinant full length Human Cytokeratin 5. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.