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PAK6 polyclonal antibody

PAK6 polyclonal antibody

Item no.	BS60321-50
Manufacturer	Bioworld Technology, Inc
Amount	50ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase PAK 6, PAK-5, p21-activated kinase 6, PAK-6, PAK6, PAK5
Similar products	PAK6
Available
Swiss-Prot	Q9NQU5
Application all	WB: 1:500ca.1:1000
Background	The p21(CDKN1A)-activated kinases (PAKs) are serine/threonine protein kinases that bind to activated small GTPases, including Cdc42 and Rac, and influence transcription, cell morphology (cytoskeleton rearrangement), motility, and apoptosis. PAK family members contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK6 protein cotranslocates into the nucleus with androgen receptor, which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development, in response to androgen. PAK6 transcripts are present at high levels in brain and testis, with lower levels in multiple tissues including prostate and breast.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	PAK6 pAb detects endogenous levels of PAK6 protein.
WB	Western blot (WB) analysis of PAK6 pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:Mouse brain tissue lysate Lane3:Rat brain tissue lysate
BiowMW	ca. 75 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Serine/threonine-protein kinase PAK 6, PAK-5, p21-activated kinase 6, PAK-6, PAK6, PAK5
Immunogen	A synthetic peptide corresponding to residues in Human PAK6.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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