Manufacturer |
Bioworld Technology, Inc
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applications |
WB |
Amount |
100ul |
Host |
Rabbit |
Item no. |
BS60313-100 |
Targets |
PI3K;;PIK3C2G |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma, PI3K-C2-gamma, Short name=PtdIns-3-kinase C2 subunit gamma, Phosphoinositide 3-kinase-C2-gamma, PI 3-kinase C2gamma, PI3KC2gamma |
Swiss-Prot |
O75747 |
Application all |
WB: 1:500ca.1:1000 |
Background |
Phosphoinositide 3-kinase activity is implicated in assorted cellular responses activated by mammalian cell surface receptors and the regulation of protein sorting in yeast. The p110gamma (PIK3CG) enzyme is activated in vitro by both the alpha and betagamma subunits of heterotrimeric GTP-binding proteins (G proteins) and does not associate with a p85 adaptor molecule. PI 3-kinase C2gamma, also designated p110gamma, may link signaling through G protein-coupled receptors to the generation of phosphoinositide second messengers that are phosphorylated in the D-3 position. The PI 3-kinase C2gamma gene encodes a 1, 050 amino acid polypeptide with 36% identity to human PI 3-kinase C2alpha. Research indicates that PI 3-kinase C2gamma can block the growth of human colon cancer cells. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
PIK3C2G pAb detects endogenous levels of PIK3C2G protein. |
WB |
Western blot (WB) analysis of PIK3C2G pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:PC12 cell lysate |
BiowMW |
ca. 171 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma, PI3K-C2-gamma, Short name=PtdIns-3-kinase C2 subunit gamma, Phosphoinositide 3-kinase-C2-gamma, PI 3-kinase C2gamma, PI3KC2gamma |
Immunogen |
A synthetic peptide corresponding to residues in Human PIK3C2G. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.