Item no. |
BS60302-50 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cytokeratin-84, Keratin, type II cuticular Hb4, Keratin-84, Keratin84, Short name=K84, Type II hair keratin Hb4, Type-II keratin Kb24, KRT84, KRTHB4 |
Similar products |
Cytokeratin 84 |
Available |
|
Swiss-Prot |
Q9NSB2 |
Application all |
WB: 1:500ca.1:1000 |
Background |
The Keratin multigene family is made of "soft" epithelial cytokeratins and "hard" hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1, 100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Cytokeratin 84 pAb detects endogenous levels of Cytokeratin 84 protein. |
WB |
Western blot (WB) analysis of Cytokeratin 84 pAb at 1:500 dilution Lane1:THP-1 cell lysate Lane2:Raw264.7 cell lysate Lane3:PC12 cell lysate |
BiowMW |
ca. 65 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Cytokeratin-84, Keratin, type II cuticular Hb4, Keratin-84, Keratin84, Short name=K84, Type II hair keratin Hb4, Type-II keratin Kb24, KRT84, KRTHB4 |
Immunogen |
A synthetic peptide corresponding to residues in Human Cytokeratin 84. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.