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c-Met (phospho-Y1349) polyclonal antibody

c-Met (phospho-Y1349) polyclonal antibody

Item no.	BS4753-100
Manufacturer	Bioworld Technology, Inc
Amount	100ul
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met, MET
Similar products	c-Met
Available
Swiss-Prot	P08581
Application all	WB: 1:500ca.1:1000
Background	c-Met, a member of the tyrosine kinase superfamily, is the receptor for hepatocyte growth factor, also known as scatter factor (HGF/SF). The mature c-Met protein is a disulfide-linked heterodimer with Mr=190 kDa composed of a heavily glycosylated alpha subunit that is completely extracellular in localization, and a beta subunit comprised of an extracellular ligand binding domain, a single transmembrane domain, and a cytoplasmic tyrosine kinase domain. Cells expressing c-Met include epithelial cells, endothelial cells, blood cells of various types, and glomerular mesenchymal cells.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	p-c-Met (Y1349) pAb detects endogenous levels of c-Met protein only when phosphorylated at Tyr1349.
WB	Western blot (WB) analysis of p-Met (Y1349) pAb at 1:500 dilution Lane1:THP-1 cell lysate treated with EGF(0.1ng/ml, 30mins) Lane2:Hela cell lysate treated with EGF(0.1ng/ml, 30mins)
BiowMW	ca. 156 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met, MET
Immunogen	Synthetic phosphopeptide derived from human c-Met around the phosphorylation site of Tyrosine 1349.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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