Item no. |
BS4673-100 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK |
Similar products |
Csk |
Available |
|
Swiss-Prot |
P41240 |
Application all |
WB: 1:500ca.1:1000 |
Background |
C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein). |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
p-Csk (S364) pAb detects endogenous levels of Csk protein when phosphorylated at Ser364. |
WB |
Western blot (WB) analysis of p-CSK (S364) pAb at 1:500 dilution Lane1:HEK293T cell lysate treated with PMA(100nM, 15min) Lane2:NIH-3T3 cell lysate treated with PMA(100nM, 15min) Lane3:H9C2 cell lysate treated with PMA(100nM, 15min) |
BiowMW |
ca. 50 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK |
Immunogen |
Synthetic phosphopeptide derived from human Csk around the phosphorylation site of Serine 364. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.