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Csk (phospho-S364) polyclonal antibody

Csk (phospho-S364) polyclonal antibody

Item no.	BS4673-100
Manufacturer	Bioworld Technology, Inc
Amount	100ul
Category	Neuroscience Neural Lineage Markers Neural Signaling Protein Aggregation, Clearance & Misfolding Neural Adhesion Molecules Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK
Similar products	Csk
Available
Swiss-Prot	P41240
Application all	WB: 1:500ca.1:1000
Background	C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	p-Csk (S364) pAb detects endogenous levels of Csk protein when phosphorylated at Ser364.
WB	Western blot (WB) analysis of p-CSK (S364) pAb at 1:500 dilution Lane1:HEK293T cell lysate treated with PMA(100nM, 15min) Lane2:NIH-3T3 cell lysate treated with PMA(100nM, 15min) Lane3:H9C2 cell lysate treated with PMA(100nM, 15min)
BiowMW	ca. 50 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK
Immunogen	Synthetic phosphopeptide derived from human Csk around the phosphorylation site of Serine 364.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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