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AR-beta3 (L291) polyclonal antibody

AR-beta3 (L291) polyclonal antibody

Item no.	BS3158-100
Manufacturer	Bioworld Technology, Inc
Amount	100ul
Category	Metabolism Diabetes Glucose Homeostasis Antibodies Obesity Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR, AR beta3, ARbeta3, beta3-AR, beta3 AR, beta3AR
Similar products	AR-beta3
Available
Swiss-Prot	P13945
Application all	WB: 1:500ca.1:1000
Background	Beta 3-adrenergic receptors (b3-ARs) bind cathecholamines (epinephrine, norepinephrine), and primarily regulate lipolysis and thermogenesis in adipose. b3-ARs are present in adipose tissues, heart, and in smooth muscle of bladder, colon, small intestine, and stomach. The human corpus cavernosum exhibits basal b3-AR-mediated vasorelaxant tone and activity is linked to inhibition of the RhoA/Rho-kinase pathway. b3-AR interacts directly with the SH3 domain of Src through proline-rich motifs (PXXP) in the third intracellular loop and the carboxy-terminus.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	AR-beta3 (L291) pAb detects endogenous levels of AR-beta3 protein.
WB	Western blot (WB) analysis of AR-beta3 (L291) pAb at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat liver tissue lysate
BiowMW	ca. 43, 68 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR, AR beta3, ARbeta3, beta3-AR, beta3 AR, beta3AR
Immunogen	Synthetic peptide, corresponding to amino acids 250-300 of Human AR-beta3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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