Item no. |
BS3031-100 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Heat shock protein beta-2, HspB2, DMPK-binding protein, MKBP, HSPB2 |
Similar products |
HSPB2 |
Available |
|
Swiss-Prot |
Q16082 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Background |
HSPB2, also called MKBP, was shown to bind and activate myotonic dystrophy protein kinase in the yeast two-hybrid system. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
HSPB2 (N143) pAb detects endogenous levels of HSPB2 protein. |
WB |
Western blot (WB) analysis of HSPB2 (N143) pAb at 1:500 dilution Lane1:Jurkat whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate |
IHC |
Immunohistochemistry (IHC) analyzes of HSPB2 (N143) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50. |
BiowMW |
ca. 20 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Heat shock protein beta-2, HspB2, DMPK-binding protein, MKBP, HSPB2 |
Immunogen |
Synthetic peptide, corresponding to amino acids 110-168 of Human HSPB2. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.