Item no. |
BS2992-50 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
50 ul |
Quantity options |
100 ul
50 ul
|
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Conjugate/Tag |
Unconjugated |
Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Catenin δ1, Catenin delta-1, Cadherin-associated Src substrate, Short name=CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384 |
Similar products |
Catenin-delta1 |
Available |
|
Application Notes |
IHC:1:50~1:200 |
Background |
The α, β, δ, and γ -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. δ-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding δ-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding δ-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. γ-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds α-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling. |
Manufacturer - Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Manufacturer - Specificity |
Catenin-δ1 (G224) polyclonal antibody detects endogenous levels of Catenin-δ1 protein. |
Molecular Weight |
~ 108 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Pathway |
Contribution of ECM and Cytoskeletal Factors to EMT |
Immunogen |
Synthetic peptide, corresponding to amino acids 201-250 of Human Catenin-δ1. |
Modification |
Unmodification |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.