Item no. |
BS2929-100 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
GDF9, GDF-9, Growth/differentiation factor 9 |
Similar products |
GDF-9 |
Available |
|
Swiss-Prot |
O60383 |
Application all |
WB: 1:500ca.1:1000
IHC: 1:50ca.1:200 |
Background |
GDF 9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF 9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
GDF-9 (E322) pAb detects endogenous levels of GDF-9 protein. |
WB |
Western blot (WB) analysis of GDF-9 (E322) pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:PC12 whole cell lysate |
IHC |
Immunohistochemistry (IHC) analyzes of GDF-9 (E322) pAb in paraffin-embedded human breast carcinoma tissue at 1:100. |
BiowMW |
ca. 51 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
GDF9, GDF-9, Growth/differentiation factor 9 |
Immunogen |
Synthetic peptide, corresponding to amino acids 301-350 of Human GDF-9. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.