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EphB1/2 (G590) polyclonal antibody

EphB1/2 (G590) polyclonal antibody

Item no.	BS1743-50
Manufacturer	Bioworld Technology, Inc
Amount	50ul
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Obesity Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ephrin type-B receptor 1, Tyrosine-protein kinase receptor EPH-2, NET, HEK-6, ELK
Similar products	EphB1/2
Available
Swiss-Prot	P54762/P29323
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 IF: 1:50ca.1:200
Background	Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	EphB1/2 (G590) pAb detects endogenous levels of EphB1/2 protein.
WB	Western blot (WB) analysis of EphB1/2 (G590) pAb in extracts from sp20 cells.
IHC	Immunohistochemistry (IHC) analyzes of EphB1/2 (G590) pAb in paraffin-embedded human brain carcinoma tissue at 1:50.
BiowMW	ca.110 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Ephrin type-B receptor 1, Tyrosine-protein kinase receptor EPH-2, NET, HEK-6, ELK
Immunogen	Synthetic peptide, corresponding to amino acids 560-610 of Human EphB1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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