Item no. |
BS1668-100 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, Short name=p75, CD122, IL2RB |
Similar products |
IL-2Rbeta |
Available |
|
Swiss-Prot |
P14784 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Background |
The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
IL-2Rbeta (T360) pAb detects endogenous levels of IL-2Rbeta protein. |
WB |
Western blot (WB) analysis of IL-2Rbeta (T360) pAb in extracts from PC12 cells. |
IHC |
Immunohistochemistry (IHC) analyzes of IL-2Rbeta (T360) pAb in paraffin-embedded human breast carcinoma tissue at 1:100. |
BiowMW |
ca.60 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, Short name=p75, CD122, IL2RB |
Immunogen |
Synthetic peptide, corresponding to amino acids 330-380 of Human IL-2Rbeta. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.