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HDAC5 (E1106) polyclonal antibody

HDAC5 (E1106) polyclonal antibody

Item no.	BS1163-50
Manufacturer	Bioworld Technology, Inc
Amount	50ul
Category	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Histone deacetylase 5, Short name=HD5, Antigen NY-CO-9, HDAC-5, KIAA0600
Similar products	HDAC5
Available
Swiss-Prot	Q9UQL6
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 IF: 1:50ca.1:200
Background	HDAC5 is a member of the class II mammalian histone deacetylase family, which is structurally related to yeast HDA1. Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence.Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	HDAC5 (E1106) pAb detects endogenous levels of HDAC5 protein.
WB	Western blot (WB) analysis of HDAC5 (E1106) pAb at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat liver tissue lysate
IHC	Immunohistochemistry (IHC) analyzes of HDAC5 (E1106) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
BiowMW	ca. 121 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Histone deacetylase 5, Short name=HD5, Antigen NY-CO-9, HDAC-5, KIAA0600
Immunogen	Synthetic peptide, corresponding to the C-terminus of Human HDAC5.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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