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PPAR-γ (E157) polyclonal antibody

PPAR-γ (E157) polyclonal antibody

Item no.	AP0688-50
Manufacturer	Bioworld Technology, Inc
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Peroxisome proliferator-activated receptor gamma, Short name=PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG, NR1C3, PPAR γ, PPARγ
Similar products	PPAR-gamma
Available
Application Notes	WB: 1:500~1:1000
Background	PPAR gamma is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPAR gamma activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPAR gamma may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPAR gamma2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPAR gamma2 gene maybe correlated with abdominal obesity in type 2 diabetes.
Manufacturer - Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Manufacturer - Specificity	PPAR-γ (E157) polyclonal antibody detects endogenous levels of PPAR gamma protein.
Molecular Weight	~ 54 kDa
Note	For research use only, not for use in diagnostic procedure.
Pathway	Nuclear Receptor Signaling, MTOR signaling
Immunogen	Synthetic peptide, corresponding to amino acids 150-200 of Human PPAR-γ.
Modification	Unmodification

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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