Manufacturer |
Bioworld Technology, Inc
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse |
Applications |
WB, IHC |
Amount |
50ul |
Host |
Rabbit |
Item no. |
BS8391-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
40S ribosomal protein S7, RPS7 |
Swiss-Prot |
P62081 |
Application all |
WB: 1:500ca.1:2000 IHC: 1:50ca.1:200 |
Background |
Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S7, also known as RPS7, is a 194 amino acid protein that is a component of the 40S subunit. Localized to the cytoplasm, Ribosomal Protein S7 belongs to the S7e family of ribosomal proteins and functions in protein synthesis. Ribosomal Protein S7 interacts with MDM2 and is believed to negatively regulate the MDM2-mediated degradation of p53. In addition, Ribosomal Protein S7 may play a role in ribosomal stress, linking ribosome biogenesis to cell death or cell cycle arrest. Like most ribosomal proteins, Ribosomal Protein S7 exists as multiple processed pseudogenes that are scattered throughout the genome. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
RPS7 polyclonal antibody detects endogenous levels of RPS7 protein. |
BiowMW |
ca. 22 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
40S ribosomal protein S7, RPS7 |
Immunogen |
Recombinant full length Human RPS7. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.