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TYMS polyclonal antibody

TYMS polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	BS71457-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	TS, TMS, HST422,
Buffer composition	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
Application info	WB 1:500 - 1:2000
Swiss-Prot	P04818
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	TYMS polyclonal antibody detects endogenous levels of TYMS protein.
BiowMW	Predicted band size: 34 kDa Observed band size: Refer to Figures
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	TS, TMS, HST422,
Immunogen	Recombinant protein of human TYMS

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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