Comparison

Integrin β3 (N-terminus) monoclonal antibody

Item no. MB0145-50
Manufacturer Bioworld Technology, Inc
Amount 50 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Monoclonal
Applications WB
Specific against Human (Homo sapiens)
Host Mouse
Conjugate/Tag Unconjugated
Purity The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Integrin beta-3, Platelet membrane glycoprotein IIIa, Short name=GPIIIa, CD_antigen=CD61, ITGB3, GP3A, CD61, GPIIIa,
Similar products Integrin beta3
Available
Application Notes
WB: 1:1000
Background
Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16α and 8β subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses.
Manufacturer - Product
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Manufacturer - Specificity
This antibody detects endogenous levels of Integrin β3 and does not cross-react with related proteins
Molecular Weight
Predicted band size :87KDa
Observed band size:110KDa
Note
For research use only, not for use in diagnostic procedure.
Pathway
Tumor Angiogenesis, Contribution of ECM and Cytoskeletal Factors to EMT
Immunogen
Synthetic peptide, corresponding to the N-terminus of Human Integrin β3.
Modification
Unmodification

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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