Manufacturer |
Bioworld Technology, Inc
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human |
Applications |
WB, IF, IHC |
Amount |
100ul |
Host |
Rabbit |
Item no. |
BS8815-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
Methyltransferase-like protein 2A, METTL2A, METTL2, HSPC266 |
Buffer composition |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Background |
METTL2A (methyltransferase like 2A) and METTL2B (methyltransferase like 2B) are 378 amino acid proteins that belong to the METL family and methyltransferase superfamily. Both proteins exist as two alternatively spliced isoforms. METTL2A is encoded by a gene that maps to human chromosome 17q23.2, and METTL2B is encoded by a gene that maps to human chromosome 7q32.1. Chromosome 7 houses over 1, 000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. |
Application info |
WB: 1:500ca.1:2000 IHC: 1:50ca.1:200 IF: 1:50ca.1:200 |
Swiss-Prot |
Q96IZ6 |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
METTL2A polyclonal antibody detects endogenous levels of METTL2A protein. |
BiowMW |
ca. 44kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Methyltransferase-like protein 2A, METTL2A, METTL2, HSPC266 |
Immunogen |
Recombinant full length Human METTL2A. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.