Item no. |
BS8763-50 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, IHC |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Histone deacetylase 5, Short name=HD5, Antigen NY-CO-9, HDAC-5, KIAA0600 |
Available |
|
Buffer composition |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Background |
HDAC5 is a member of the class II mammalian histone deacetylase family, which is structurally related to yeast HDA1. Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence.Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions. |
Application info |
WB: 1:500ca.1:2000 IHC: 1:50ca.1:200 IF: 1:50ca.1:200 |
Swiss-Prot |
Q9UQL6 |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
HDAC5 polyclonal antibody detects endogenous levels of HDAC5 protein. |
BiowMW |
ca. 122kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Histone deacetylase 5, Short name=HD5, Antigen NY-CO-9, HDAC-5, KIAA0600 |
Immunogen |
Recombinant full length Human HDAC5. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.