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TNF-beta / LTA polyclonal antibody

TNF-beta / LTA polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neuroinflammation Metabolism Diabetes Antibodies Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Applications	WB, IHC
Amount	100ul
Host	Rabbit
Item no.	BS6840-100
Targets	LTA ;; TNF
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	Lymphotoxin-alpha, LT-alpha, TNF-beta, Lymphotoxin alpha, LTalpha, TNFbeta, Tumor necrosis factor ligand superfamily member 1, LTA, TNFB, TNFSF1
Swiss-Prot	P01374
Application all	WB: 1:500ca.1:2000 IHC: 1:50ca.1:200
Background	Tumor necrosis factor b (TNFb), also known as lymphotoxin, is a pleiotropic cytokine. TNFa, also known as cachectin, is a smaller cytokine that binds to the same receptors, producing a vast array of effects similar to those of TNFb. TNFb and TNFa share 30% amino acid homology and have similar biological activities. TNFb is produced by activated lymphocytes, including CD4(+) T helper cell type 1 lymphocytes, CD8(+) lymphocytes and certain B lymphoblastoid cell lines. TNFa is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFa and TNFb can modulate many immune and inflammatory functions, while having the ability to inhibit tumor growth.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	LTA pAb detects endogenous levels of LTA protein.
WB	Western blot (WB) analysis of TNF-beta / LTA pAb
BiowMW	ca. 22 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Lymphotoxin-alpha, LT-alpha, TNF-beta, Lymphotoxin alpha, LTalpha, TNFbeta, Tumor necrosis factor ligand superfamily member 1, LTA, TNFB, TNFSF1
Immunogen	Recombinant full length Human TNF-beta.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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