« Back
Home /
KEAP1 Polyclonal Antibody

KEAP1 Polyclonal Antibody

Item no.	BM-CAC07039-100ug
Manufacturer	Biomatik
Amount	100ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Adenocarcinoma Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC, ELISA
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Kelch-like ECH-associated protein 1,Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19,KEAP1,INRF2, KIAA0132, KLHL19
Available
Immunogen	Recombinant human Kelch-like ECH-associated protein 1 protein (1-624AA)
Conjugate	Unconjugated
Alternative Names	Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19, KEAP1, INRF2, KIAA0132, KLHL19
UniProt ID	Q14145
Purification	Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Instructions	Aliquot and store at -20C. Minimize freezing and thawing.
Expiry Date	1 year
Shipping Condition	Blue ice
Comment	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100ug

available

Delivery expected until 8/30/2024

Express Delivery: Save 2 days

Compare

Add to wishlist

Recommend by mail