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Cleaved PARP Monoclonal Antibody

Cleaved PARP Monoclonal Antibody

Item no.	BM-CAK71359-30ug
Manufacturer	Biomatik
Amount	30ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IF, IHC
Specific against	Human
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Clonality	Monoclonal
Isotype info	Mouse IgG1
Immunogen	Synthetic Peptide
Conjugation	Unconjugated
Alternative Names	PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD (+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Gene ID	142
Accession Number	P09874
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration	1 mg/ml
Storage	-20°C
Expiry Date	1 year
Shipping Condition	Ice packs
Comments	PARP1 encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, poly (ADP-ribose) polymerase 1 may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Technical Notes	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:2000-5000.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 30ug

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Delivery expected until 11/1/2024

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