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Anti-Mouse/Rat CD40 FITC

Anti-Mouse/Rat CD40 FITC

Item no.	02512-50-100
Manufacturer	BioGems
Amount	100 ug
Category	Neuroscience Neural Lineage Markers Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	FITC
Applications	FC
Clone	HM40-3
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Hamster - Armenian
Isotype	IgM Kappa
Conjugate/Tag	FITC
Citations	Kaneko, Y., Hirose, S., Abe, M., Yagita, H., Okumura, K., & Shirai, T. (1996). CD40-mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus. European journal of immunology, 26(12), 3061-3065. Ferlin, W. G., Severinson, E., Sträm, L., Heath, A. W., Coffman, R. L., Ferrick, D. A., & Howard, M. C. (1996). CD40 signaling induces interleukin-4-independent IgE switching in vivo. European journal of immunology, 26(12), 2911-2915. Kashiwada, M., Kaneko, Y., Yagita, H., Okumura, K., & Takemori, T. (1996). Activation of mitogen-activated protein kinases via CD40 is distinct from that stimulated by surface IgM on B cells. European journal of immunology, 26(7), 1451-1458.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 5/22/2025

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