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Anti-Mouse CD41 PE 50 ug

Anti-Mouse CD41 PE 50 ug

Item no.	03512-60-50
Manufacturer	BioGems
Amount	50 ug
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Lung Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	MWReg30
Specific against	Mouse
Host	Rat
Isotype	IgG1 kappa
Conjugate/Tag	PE
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb. It is expressed on hematopoietic progenitors, megakaryocytes, and platelets. It forms a receptor with CD61 (integrin beta 3) that binds adhesion molecules such as fibrinogen, fibronectin, von Willebrand factor, and thrombin. Defects or absence of CD41 has been found to lead to coagulation disorders. The expression profile of CD150+, CD48-, and CD41- can be used to identify hematopoietic stem cells.
Research Interest	Stem Cells
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References	Schmidt, R. E., Grau, G. E., Männel, D. N., Nieswandt, B., Echtenacher, B., Wachs, F. P., ... & Gessner, J. E. (1999). Acute Systemic Reaction and Lung Alterations Induced by an Antiplatelet. Blood, 94(2), 684-693. Bertrand, J. Y., Giroux, S., Golub, R., Klaine, M., Jalil, A., Boucontet, L., ... & Cumano, A. (2005). Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin. Proceedings of the National Academy of Sciences of the United States of America, 102(1), 134-139. Mitjavila-Garcia, M. T., Cailleret, M., Godin, I., Nogueira, M. M., Cohen-Solal, K., Schiavon, V., ... & Vainchenker, W. (2002). Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells.Development, 129(8), 2003-2013.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 8/23/2024

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