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Anti-Mouse CD90.2 BG Violet 450

Anti-Mouse CD90.2 BG Violet 450

Item no.	03012-40-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Development Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Primary Antibodies By Organ Brain Cancer
Type	Antibody
Format	BG Violet 450
Applications	FC
Clone	30-H12
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b
Conjugate/Tag	BG Violet 450
Citations	Ledbetter, J. A., & Herzenberg, L. A. (1979). Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens. Immunological reviews, 47(1), 63-90. Radrizzani, M., Carminatti, H., Pivetta, O. H., & Vargas, V. P. (1995). Developmental regulation of Thy 1.2 rate of synthesis in the mouse cerebellum.Journal of neuroscience research, 42(2), 220-227. Seaman, W. E., Wofsy, D., Greenspan, J. S., & Ledbetter, J. A. (1983). Treatment of autoimmune MRL/Ipr mice with monoclonal antibody to Thy-1.2: a single injection has sustained effects on lymphoproliferation and renal disease.The Journal of Immunology, 130*(4), 1713-1718.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.2, expressed on thymocytes, mature T cells, epithelial cells, neurons, hematopoietic stem cells, and fibroblasts. CD90 is a membrane glycoprotein that regulates the adhesion and signal transduction in T lymphocytes, and the adhesion of thymocytes to thymic stroma. The interaction between 30-H12 and the antibody to the CD3/TCR complex upregulates thymocytes signal transduction and apoptosis and downregulates mature T cell proliferation. The 30-H12 antibody seems to be unable to cross-link with CD90.1. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity
Manufacturers conjugate	BG Violet 450

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 5/22/2025

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