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Anti-Mouse F4/80 Antigen PerCP-Cy5.5 Size 25 ug

Anti-Mouse F4/80 Antigen PerCP-Cy5.5 Size 25 ug

Item no.	02922-70-25
Manufacturer	BioGems
Amount	25 ug
Category	Oncology Neuroscience Neuroinflammation Antibodies Flow Cytometry Primary Antibodies By Organ Bone Cancer
Type	Antibody
Format	PerCP-Cy5.5
Applications	FC
Clone	BM8.1
Specific against	Mouse
Host	Rat
Isotype	IgG2a kappa
Conjugate/Tag	PerCP/Cy5.5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The BM8.1 monoclonal antibody specifically binds to the Mouse125 kDa F4/80 antigen, expressed by most mature macrophages. F4/80 is a transmembrane protein used as a marker of macrophages, although it is also expressed on Kupffer and Langerhans cells. The expression of F4/80 antigen is upregulated on bone marrow cells stimulated in vitro with the macrophage colony stimulating factor. The F4/80 antigen is a requirement for the induction of CD8 T cells-mediated peripheral tolerance.
Research Interest	Innate Immunity
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References	Zwadlo, G., Bräcker, E. B., Von Bassewitz, D. B., Feige, U., & Sorg, C. (1985). A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes. The Journal of Immunology, 134(3), 1487-1492. Leenen, P. J., de Bruijn, M. F., Voerman, J. S., Campbell, P. A., & van Ewijk, W. (1994). Markers of mouse macrophage development detected by monoclonal antibodies. Journal of immunological methods, 174(1), 5-19. Schaller, E., Macfarlane, A. J., Rupec, R. A., Gordon, S., McKnight, A. J., & Pfeffer, K. (2002). Inactivation of the F4/80 glycoprotein in the mouse germ line.Molecular and cellular biology, 22(22), 8035-8043.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 ug

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Delivery expected until 9/20/2024

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