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Anti-Human CD3 SAFIRE Size 500 ug

Anti-Human CD3 SAFIRE Size 500 ug

Item no.	05131-25-500
Manufacturer	BioGems
Amount	500 ug
Category	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Applications	WB, FC, IF, IP, IHC
Clone	UCHT1
Specific against	Human
Host	Mouse
Isotype	IgG1 kappa
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ , δ , and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε . The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.
Research Interest	Adaptive Immunity
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References	Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. McMichael, A. J. (1987). Leucocyte typing III. Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985) Beverley, P. C., & Callard, R. E. (1981). Distinctive functional characteristics of human T lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. European journal of immunology, 11(4), 329-334.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 8/23/2024

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