AG1557

Item no.	HY-12806-100mg
Manufacturer	MedChem Express
CASRN	189290-58-2
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Biochemicals
Specific against	other
Purity	99.63
Formula	C16H14IN3O2
Citations	[1]Ellis AG, et al. High-performance liquid chromatographic analysis of the tyrphostin AG1478, a specific inhibitor of the epidermal growth factor receptor tyrosine kinase, in mouse plasma. J Chromatogr B Biomed Sci Appl. 2001 Apr 15;754(1):193-9.<br>[2]Akshada Joshi, et al. Identification of Potential Novel EGFR Inhibitors using a Combination of Pharmacophore and Docking Methods. International Journal of Pharmacy and Pharmaceutical Sciences, ISSN- 0975-1491 Vol 7, Issue 6, 2015
Smiles	COC1=CC2=NC=NC(NC3=CC=CC(I)=C3)=C2C=C1OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	AG1557 is a specific and ATP competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase, has a pIC50 value of 8.194[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	407.21
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 83.33 mg/mL (ultrasonic)
Manufacturers Target	EGFR
Pathway	JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Request delivery time