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PXS 4728A

PXS 4728A

Item no.	B2693-054564
Manufacturer	BOC Sciences
CASRN	1478364-68-9
Amount	100mg
Specific against	other
Purity	98%
Formula	C15H21FN2O2.HCl
InCHI	1S/C15H21FN2O2.ClH/c1-15(2,3)18-14(19)12-4-6-13(7-5-12)20-10-11(8-16)9-17;/h4-8H,9-10,17H2,1-3H3,(H,18,19);1H/b11-8+;
Smiles	CC(C)(C)NC(=O)C1=CC=C(C=C1)OCC(=CF)CN.Cl
Alias	BI-1467335 HCl; (E)-4-((2-(aminomethyl)-3-fluoroallyl)oxy)-N-(tert-butyl)benzamide hydrochloride
Available
Information/Product description	PXS 4728A is a VAP-1 (aka SSAO/AOC3) inhibitor with IC50 values 5 nM in the clinical trial for the treatment of non-alcoholic steatohepatitis (NASH). Studies show that it inhibits neutrophil rolling and tethering in mouse cremaster model, and alleviates respiratory inflammation in multiple models.
Manufacturers Category / Type	Chemicals/Reagents & Chemicals
Product Origin	USA

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