Manufacturer |
AVIVA Systems Biology
|
Category |
|
Type |
Proteins |
Specific against |
other |
Format |
S100A1 in 20mM Tris-HCl, pH7.0 and 0.1mM EDTA. Physical appearance: Sterile Filtered clear solution. |
Amount |
5ug |
Host |
E.coli |
Item no. |
OPPA01277 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Alias |
Protein S100-A1, S100 calcium-binding protein A1, S-100 protein alpha subunit, S-100 protein alpha chain, S100A1, S100A, S100, S100-alpha, S100-A1, S100A1 Human, S100 Calcium Binding Protein A1 Human Recombinant |
Gene symbol |
S100A1 |
Protein name |
Protein S100-A1 |
Product format |
The S100A1 protein was lyophilized from 0.4um filtered solution at a concentration of 0.5mg/ml containing 20mM Tris pH-7.5 and 50mM NaCl. Physical appearance: White lyophilized (freeze-dried) powder. |
Gene id |
6271 |
Reconstitution and storage |
Reconstitution: Add deionized water to a working concentration approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by appropriate sterile filter before using it in the cell culture. Storage: Lyophilized S100A1 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution S100A1 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Description of target |
S100A1 is a member of the S100 family of calcium binding proteins with EF-hand type Ca+2 binding motive. S100A1 (Calcium Binding Protein A1) is involved in the activation of sarcoplasmatic calcium release and the regulation of intermediate filament polymerization. S100A1 may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of S100A1 has been implicated in cardiomyopathies. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. |
Purification |
S100A1 Human Recombinant is purified by proprietary chromatographic techniques. |
Purity |
Greater than 95.0% as determined by SDS-PAGE. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.