Comparison

SCF Protein (OPPA00540)

Item no. OPPA00540
Manufacturer AVIVA Systems Biology
Amount 2ug
Category
Type Proteins
Format Lyophilized from a concentrated (1mg/ml) solution in water containing 10mM Sodium phosphate buffer pH=6.5. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against other
Host E.coli
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250, Hematopoietic growth factor KL, Steel factor, SCF Mouse, Recombinant Mouse Stem Cell Factor
Similar products mSCF
Available
Gene symbol
mSCF
Protein name
Kit ligand
Molecular weight
18 kDa
Product format
Lyophilized from a concentrated solution in water containing 0.02% NaHCO3
Physical Appearance: Sterile filtered white freeze-dried powder
Gene id
17311
Reconstitution and storage
It is recommended to reconstitute the lyophilized Stem Cell Factor in sterile 18M-omega-cm H2O not less than 100 ug/mL, which can be further diluted to other aqueous solutions. Lyophilized KIT ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution SCF should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target
Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid).
Purification
Purified by proprietary chromatographic techniques.
Biological activity
The ED50 as determined by the dose-dependent stimulation of Human TF-1 cell line is <10 ng/ml, corresponding to a Specific Activity of 1x105 IU/mg.
Purity
Greater than 98.0% as determined by (a) Analysis by SEC-HPLC (b) Analysis by SDS-PAGE

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2ug
Available: In stock
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