MYO1G Recombinant Protein (OPCD05547)

MYO1G

34 kDa

246177

Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration . Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication . Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes . Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis .

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.